Veteran? See how the VA covers ketamine treatment — read our guide.

Ketamine Therapy & IV Infusions in Jacksonville, FL

When other treatments have not brought the relief you need

If other treatments haven’t helped enough, a consultation can help you understand whether IV ketamine is an option for you. At our San Marco clinic, care begins with a review of your history, symptoms and goals.

Call (904) 877-1100
  • ✦ Psychiatric-led
  • ✦ Private monitored rooms
  • ✦ In person or Zoom consult
Patient relaxing in a private infusion chair at The Practice
Monarch butterfly resting on an orange flower

$49

Consultation, applied toward treatment

Who treatment may help

Could ketamine be an option for you?

IV ketamine is used off-label for treatment-resistant depression, anxiety, PTSD, and certain chronic pain conditions. A consultation determines whether treatment is appropriate for your history and needs.

Woman resting with eyes closed in soft light

Treatment-resistant depression

When two or more antidepressants have not brought enough relief — the most common reason people seek IV ketamine in Jacksonville.
Wooden blocks turning the word panic into calm

Anxiety disorders

Persistent anxiety, panic, and nervous-system activation that has not responded fully to standard care.
Patient receiving a monitored IV infusion

PTSD & trauma

Trauma-informed infusion care for hypervigilance, flashbacks, and treatment-resistant PTSD symptoms — including veterans.
Illustration of nerve pain in the legs

Chronic pain

CRPS, neuropathy, migraines, and centralized pain with longer, pain-focused infusion protocols.

What to expect

Your care, step by step

Most patients with depression, anxiety, or PTSD begin with an induction series of six IV infusions over about four weeks. Chronic-pain protocols use longer sessions and are quoted separately.

  1. Psychiatric provider at his desk in the clinic 01

    Clinical consultation

    In person in San Marco or via Zoom. We review your history, medications tried and goals, and tell you honestly whether ketamine fits.

  2. Calm private room at The Practice with soft seating 02

    Monitored treatment

    Typically six infusions over about four weeks for mood protocols, each in a private room with continuous vitals and psychiatric oversight.

  3. Woman breathing in fresh air by the ocean 03

    Reviewing your response

    We track symptoms across the series and adjust the plan with you. If treatment helps, occasional boosters may follow.

Plan for a ride home after each infusion. Read more about the treatment experience.

6
Infusions over about four weeks
1:1
Private room, continuous vitals
Charles Maddix, PMHNP-BC, in his office at The Practice

A provider who understands your whole history

Your consultation is with the psychiatric provider who will direct your care. Infusions take place in a private room with continuous vitals monitoring and board-certified psychiatric oversight. Meet our providers.

Candidacy

Who is a good candidate for ketamine therapy?

Ketamine infusion therapy is not first-line for everyone. A board-certified psychiatric provider confirms fit after reviewing your history — including medications tried, medical risks, and goals.

This may be a fit if you…

  • You have tried two or more antidepressants or therapies without adequate relief
  • Depression, anxiety, or PTSD still interferes with work, relationships, or daily life
  • You can arrange a ride home after each infusion and commit to a short induction series

It may not be right if you…

  • Uncontrolled high blood pressure or certain heart conditions (screened at consult)
  • Active psychosis or some unstable psychiatric presentations
  • Pregnancy, or a substance-use history that needs a different level of care first
  • Emergency or crisis needs — call 911 or 988; this is not an ER service

In their own words

Hear it from our ketamine patients

Two patients from our Jacksonville clinic talk about life before treatment, what the infusions were like, and what changed afterward.

After a lifelong struggle with depression, Lori describes what ketamine infusion therapy changed.
Jackie shares their experience with ketamine infusion therapy at The Practice.

Shared with each patient's permission. Individual results vary.

Costs & next steps

Know the cost before you commit to a series

  • Consultation

    Applied toward treatment if you continue; refunded if you are not a candidate.

    $49

  • Six-infusion seriesMost chosen

    $479 per infusion. The standard induction for depression, anxiety and PTSD.

    $2,874

  • Ten-infusion series

    $399 per infusion.

    $3,990

Single booster $549, only for clients who completed an induction protocol of six infusions in four weeks with The Practice. Chronic-pain protocols are quoted separately. IV ketamine is self-pay; insurance reimbursement is not guaranteed. Full pricing, financing & insurance details.

Comparing options? Our IV ketamine vs. Spravato guide explains the differences and research limitations. Individual results vary, and neither treatment is right for everyone.

The Practice’s light-filled lobby with a red armchair

Common questions

Ketamine infusion therapy FAQs — Jacksonville patients

What conditions can ketamine therapy help with?

Ketamine infusion therapy at The Practice may help with treatment-resistant depression, anxiety disorders, PTSD, and certain chronic pain conditions. Suitability is determined in a comprehensive consultation with the board-certified psychiatric provider who will oversee your infusions in Jacksonville’s San Marco.

Does insurance cover ketamine infusions?

IV ketamine is used off-label for mood conditions, while Spravato (esketamine nasal spray) is FDA-approved for treatment-resistant depression. If an on-label nasal-spray option is a better fit for your situation, we will say so.

How many ketamine treatments for depression will I need?

Most patients begin with an induction series of six monitored IV infusions over about four weeks. Many notice change within the first few sessions. Responders often continue with occasional single booster infusions. Your exact plan is personalized at consultation.

Who is a good candidate for ketamine therapy?

Adults with depression, anxiety, or PTSD that has not responded adequately to standard treatments — and who can complete a medical evaluation and arrange a ride home after each infusion. Uncontrolled blood pressure, certain heart conditions, active psychosis, pregnancy, and some substance-use histories may exclude candidacy until cleared.

What does a ketamine infusion session feel like?

Most patients describe a relaxed, dream-like state. You remain conscious in a private, monitored room. Mild temporary dissociation can occur and typically fades within about an hour. Read our what-to-expect guide for an hour-by-hour walkthrough.

Is ketamine therapy safe?

In a monitored clinical setting with trained providers, ketamine has a strong safety profile built on decades of medical use. At The Practice every infusion is run by a board-certified psychiatric provider or psychiatrist with continuous blood pressure, heart rate, and oxygen monitoring.

How do I start ketamine therapy near me in Jacksonville?

Book a consultation — online or by calling (904) 877-1100 — in person at 3547 Hendricks Ave in San Marco or via Zoom. We review your history, confirm fit, and explain the treatment plan before anything begins.

More questions answered on our full ketamine FAQ, including safety details and booking logistics.

Northeast Florida

Ketamine clinic in Jacksonville’s San Marco — serving the First Coast

The Practice is a veteran-owned medical clinic at 3547 Hendricks Ave in Jacksonville’s San Marco district. Arrange a ride home after each infusion. Consultations are available in person or via Zoom.

Call (904) 877-1100 or book a consultation online. LegitScript certified. Get directions to our San Marco clinic on Google Maps.

Woman breathing in fresh air by the ocean

Let’s talk about what comes next

Start with a $49 consultation in San Marco or via Zoom. We’ll review your history and tell you honestly whether ketamine is a fit.