Testosterone Replacement Therapy: Pellets or Injections?

Headshot of Charles Maddix APRN, MSN, PMHNP-BC
Charles Maddix, APRN, MSN, PMHNP-BC
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December 22, 2022

In modern testosterone replacement therapy (TRT), men have traditionally looked to testosterone injections to get the results they desire.


But while injections may be the go-to solution, a growing number of men are turning to pellets for their testosterone delivery needs. Those suffering from low testosterone symptoms - such as fatigue, low libido, and poor concentration- can often find greater relief with pellets.


Testosterone pellets - implanted directly under the skin - offer a host of benefits that injections are unable to match, making them an ideal choice for men looking to balance their hormone levels

But how do these two treatments compare? And how can you know if you are a good candidate for testosterone pellets? Let’s take a look at the differences between pellets and injections - and see why pellets are quickly becoming the preferred choice for testosterone replacement therapy (TRT).


What Are Testosterone Pellets?

Testosterone pellets are small, rice-sized pellets made with crystalline testosterone. Once implanted under the skin, they slowly dissolve releasing a steady stream of testosterone over a period of several months.


When compared to testosterone injections, the benefits of pellets are:

●      Mental clarity: Injections often come with peaks and troughs that can lead to mood swings, anxiety, low libido, and other symptoms. Pellets provide a steady stream of testosterone, so you feel more balanced and focused throughout the day.

●      Energy boosts: Pellets help your body make better use of testosterone, which can result in a more muscular, healthier physique and more energy through out the day.

●      Enhanced physical performance and libido: Pellets keep testosterone at optimal levels, day and day out, so physical performance and libido don't take a dive due to a crashing testosterone levels. Injections come with a peak and then a trough as testosterone levels fall after a week or two and it's time for another injection.

●      Improved skin and hair: Increased, sustained testosterone can result in improved skin and hair.


Let's take a deeper dive into pellet therapy is quickly becoming the preferred choice for testosterone replacement:

Pellets Offer an Enhanced Duration Of Action

One of the significant differences between pellets and injections is the duration of action. Traditional testosterone injections need to be administered every 1-2 weeks in order to keep testosterone levels balanced - meaning multiple visits to the doctor throughout the year.

Pellets, on the other hand, are designed to last up to 90 days - meaning only 4 visits will get you taken care of for an entire year. Pellet therapy has become a truly time-saving option for busy men who want the benefits of TRT without the inconvenience.

Pellet TRT Therapy Offers Greater Treatment Stability

Because pellets release a constant, steady stream of testosterone over time, they provide much more stability in testosterone levels than injections can. This means fewer spikes and troughs - and that ultimately avoids many of the worst side effects associated with traditional injection therapy.

This means you can get the desired results without worrying about the hormonal fluctuations that often occur with injections. These fluctuations can lead to mood swings, weight gain, and prostate enlargement. Pellets work to deliver a balanced level of testosterone that keep you feeling great.

Pellets Are Proven Safe & Effective

Pellets have also been proven to be highly safe and effective - making them an attractive choice for many men when it comes to testosterone replacement therapy. In fact, studies have found that patients who received pellet therapy had significantly greater overall satisfaction than those receiving injections.

The process begins with a standard consultation and blood test to make sure you’re a candidate for TRT. After that, the pellets are implanted under the skin - and you’re free to go about your daily life. Over the next few months, the pellets will dissolve and release the testosterone your body needs to feel its best.

Discover Your Ideal TRT Options With The Practice

When it comes to testosterone replacement therapy, pellets provide a number of advantages over injections. From the convenience of fewer doctor visits to the stability and safety they offer - pellets are quickly becoming the preferred choice for hormone replacement.

At The Practice, our team of experts is dedicated to helping you find the right treatment option for your needs. With our cutting-edge technology and personalized approach, we can help you reach your goals and get back on track with a customized plan that works for you.

We utilize Pellecome® bioidentical pellets to provide safe and effective testosterone replacement therapy. After your initial consultation, we will work together to create a plan that’s tailored to your needs, so you can enjoy all the benefits of TRT while avoiding any potential side effects.

Best of all, most Pellecome® appointments only take 15 minutes - so you can get back to your day quickly and start feeling the effects of hormone replacement therapy in no time.

Schedule your consultation with The Practice today and discover what testosterone replacement therapy can do for you! We look forward to helping you reach your goals and get back on track with a customized plan that works for you. When you experience the difference Pellecome® pellets can make, you won’t look back. Contact us today 904.877.1100, info@thepractice.co.

Charles Maddix is the Owner & CEO of The Practice.  A private practice focused on the well-being of the individual as a whole, mind and body.

Among the unique modalities offered by The Practice are:

Ketamine Infusion therapy– Ketamine infusion therapy involves the administration of a series of infusions for the management of psychiatric disorders like major depressive disorder, post-traumatic stress disorder, and acute suicidality.  Working very quickly — in many, often within hours — to ease symptoms.

Bioidentical hormone replacement therapy - Bioidentical hormone replacement therapy (BHRT) uses hormones that are chemically identical to the hormones naturally produced in the human body. Derived from plant sources and formulated to match the molecular structure of hormones produced by the body. BHRT is used to treat symptoms of hormonal imbalances, in both men and women.

NeuroStar® TMS – NeuroStar® TMS delivers our advanced and unique form of TMS (transcranial magnetic stimulation), a non-invasive therapy that uses targeted magnetic pulses to stimulate areas of the brain that are underactive in people suffering from depression.

Opioid Replacement Therapy - Opioid replacement therapy (ORT) is an effective treatment for addiction to opioid drugs such as heroin, oxycodone, hydromorphone (Dilaudid), fentanyl and Percocet. The therapy involves taking the opioid agonists buprenorphine (Suboxone). This medication works to prevent withdrawal and reduce cravings for opioid drugs.

Invega Sustena – a once-monthly injection treatment approved by the FDA for bipolar 1 disorder maintenance. This eliminates the need for daily oral medications in appropriate patients.Allergy Immunotherapy -

Allergen immunotherapy, also known as allergy shots, is a long-term treatment that decreases symptoms for many people with allergies often leading to lasting relief of allergy symptoms even after treatment is stopped. This makes it a cost-effective, beneficial treatment approach for many people.

Please call 904.877.1100 if you are interested in any of our services or would like to schedule an appointment.  Visit us at thepractice.co to learn more!